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Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae

Received: 6 July 2016     Accepted: 12 July 2016     Published: 10 January 2017
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Abstract

The fractions and pure compounds isolated from the bark of R. heudoletti were tested for their antibacterial properties on negative and positive gram bacteria using the disc diffusion method. Phytochemical analysis of the fractions and pure compound isolated was also conducted. The inhibitions parameters of the fractions and pure compound were determined using macro dilution method. The results showed that fraction and isoflavonoid exhibited a significant antibacterial effect against twelve strains isolated from patients. These micro-organisms were Gram-negative (Escherichia coli, Salmonella typhi, Shigella flexneri, Pseudomonas aeroginosa, Enterobacter cloacae, Klebsiella pneumoniae, Klebsiella oxytoca, Morganella morganii, Citrobacter freundi, and Proteus vulgaris) and positive gram (Staphylococcus aureus, and Streptococcus feacalis). The ratio of minimal bactericidal concentration (MBC) over the minimal inhibitory concentration (MIC) indicated a promising bactericidal effect of fractions and pure compounds isolated. These results support the current common use of the bark of Ricinodendron heudoletti and flavonoids in the treatment of some infectious diseases.

Published in Journal of Diseases and Medicinal Plants (Volume 2, Issue 6)
DOI 10.11648/j.jdmp.20160206.14
Page(s) 83-89
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Biochemistry Properties, Flavonoids, Infectious Diseases, Ricinodendron heudoletti

References
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Cite This Article
  • APA Style

    Oyono Victor, Fokunang Charles, Tembe-Fokunang Estella, Tsague Marthe, Messi Angélique, et al. (2017). Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae. Journal of Diseases and Medicinal Plants, 2(6), 83-89. https://doi.org/10.11648/j.jdmp.20160206.14

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    ACS Style

    Oyono Victor; Fokunang Charles; Tembe-Fokunang Estella; Tsague Marthe; Messi Angélique, et al. Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae. J. Dis. Med. Plants 2017, 2(6), 83-89. doi: 10.11648/j.jdmp.20160206.14

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    AMA Style

    Oyono Victor, Fokunang Charles, Tembe-Fokunang Estella, Tsague Marthe, Messi Angélique, et al. Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae. J Dis Med Plants. 2017;2(6):83-89. doi: 10.11648/j.jdmp.20160206.14

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  • @article{10.11648/j.jdmp.20160206.14,
      author = {Oyono Victor and Fokunang Charles and Tembe-Fokunang Estella and Tsague Marthe and Messi Angélique and Assam Jean and Ngameni Bethelemy and Kechia Frederick and Armel Herve Nwabo Kamdje and Penlap Veronique and Ngadjui Bonaventure},
      title = {Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae},
      journal = {Journal of Diseases and Medicinal Plants},
      volume = {2},
      number = {6},
      pages = {83-89},
      doi = {10.11648/j.jdmp.20160206.14},
      url = {https://doi.org/10.11648/j.jdmp.20160206.14},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jdmp.20160206.14},
      abstract = {The fractions and pure compounds isolated from the bark of R. heudoletti were tested for their antibacterial properties on negative and positive gram bacteria using the disc diffusion method. Phytochemical analysis of the fractions and pure compound isolated was also conducted. The inhibitions parameters of the fractions and pure compound were determined using macro dilution method. The results showed that fraction and isoflavonoid exhibited a significant antibacterial effect against twelve strains isolated from patients. These micro-organisms were Gram-negative (Escherichia coli, Salmonella typhi, Shigella flexneri, Pseudomonas aeroginosa, Enterobacter cloacae, Klebsiella pneumoniae, Klebsiella oxytoca, Morganella morganii, Citrobacter freundi, and Proteus vulgaris) and positive gram (Staphylococcus aureus, and Streptococcus feacalis). The ratio of minimal bactericidal concentration (MBC) over the minimal inhibitory concentration (MIC) indicated a promising bactericidal effect of fractions and pure compounds isolated. These results support the current common use of the bark of Ricinodendron heudoletti and flavonoids in the treatment of some infectious diseases.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - Phytochemical Screening and Biological Activity Studies of the Extract from the Bark of Ricinodendron heudoletti, Euphorbiaceae
    AU  - Oyono Victor
    AU  - Fokunang Charles
    AU  - Tembe-Fokunang Estella
    AU  - Tsague Marthe
    AU  - Messi Angélique
    AU  - Assam Jean
    AU  - Ngameni Bethelemy
    AU  - Kechia Frederick
    AU  - Armel Herve Nwabo Kamdje
    AU  - Penlap Veronique
    AU  - Ngadjui Bonaventure
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    N1  - https://doi.org/10.11648/j.jdmp.20160206.14
    DO  - 10.11648/j.jdmp.20160206.14
    T2  - Journal of Diseases and Medicinal Plants
    JF  - Journal of Diseases and Medicinal Plants
    JO  - Journal of Diseases and Medicinal Plants
    SP  - 83
    EP  - 89
    PB  - Science Publishing Group
    SN  - 2469-8210
    UR  - https://doi.org/10.11648/j.jdmp.20160206.14
    AB  - The fractions and pure compounds isolated from the bark of R. heudoletti were tested for their antibacterial properties on negative and positive gram bacteria using the disc diffusion method. Phytochemical analysis of the fractions and pure compound isolated was also conducted. The inhibitions parameters of the fractions and pure compound were determined using macro dilution method. The results showed that fraction and isoflavonoid exhibited a significant antibacterial effect against twelve strains isolated from patients. These micro-organisms were Gram-negative (Escherichia coli, Salmonella typhi, Shigella flexneri, Pseudomonas aeroginosa, Enterobacter cloacae, Klebsiella pneumoniae, Klebsiella oxytoca, Morganella morganii, Citrobacter freundi, and Proteus vulgaris) and positive gram (Staphylococcus aureus, and Streptococcus feacalis). The ratio of minimal bactericidal concentration (MBC) over the minimal inhibitory concentration (MIC) indicated a promising bactericidal effect of fractions and pure compounds isolated. These results support the current common use of the bark of Ricinodendron heudoletti and flavonoids in the treatment of some infectious diseases.
    VL  - 2
    IS  - 6
    ER  - 

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Author Information
  • Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon

  • Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon

  • Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon

  • Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon

  • Department of Biochemistry, Faculty of Sciences, University of Yaounde 1, Yaounde, Yaounde, Cameroon

  • Department of Biochemistry, Faculty of Sciences, University of Douala, Douala, Cameroon

  • Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon

  • Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon

  • Department of Biological Sciences, University of Ngaoundere, Ngaoundere, Cameroon

  • Department of Biochemistry, Faculty of Sciences, University of Yaounde 1, Yaounde, Yaounde, Cameroon

  • Department of Pharmaceutical Sciences and Traditional Pharmacopeia, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde, Cameroon

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